Squaresoft’s Parasite Eve was based on a popular Japanese book written by pharmacologist Hideaki Sena in his free time. Doing testing on mitochondria cells, producers of electrical energy in organisms, he started to wonder about the results if mitochondria decided it had had enough and took over the bodies it was residing in. 

Sena was happy with the video game adaptation of his work, an adaptation that went on to big success in its own right, and spawned two sequels. 

All NYPD cop Ms. Brea wanted was an evening at the opera without the actors and audience spontaneously bursting into flame. Unfortunately, as we see in this horrifying PlayStation game intro, she didn’t get her wish.